metformin: current knowledge

نویسندگان

hamid nasri

mahmoud rafieian-kopaei

چکیده

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Metformin: Current knowledge

Diabetes mellitus is a group of metabolic disorders in which the blood glucose is higher than normal levels, due to insufficiency of insulin release or improper response of cells to insulin, resulting in high blood pressure. The resultant hyperglycemia produces sever complications. Metformin drug has been shown to prevent diabetes in people who are at high risk and decrease most of the diabetic...

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Metformin Pharmacogenomics: Current Status and Future Directions

The incidence of type 2 diabetes (T2D) and its costs to the health care system continue to rise. Despite the availability of at least 10 drug classes for the treatment of T2D, metformin remains the most widely used first-line pharmacotherapy for its treatment; however, marked interindividual variability in response and few clinical or biomarker predictors of response reduce its optimal use. As ...

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Another animal to human transmission of a coronavirus occurred in December 2019 on a live animal market in the Chinese city of Wuhan causing an epidemic in China, reaching now different continents. This minireview summarizes the research literature on the virological, clinical and epidemiological aspects of this epidemic published until end of February 2020.

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In the individuals previously uninfected by M.tuberculosis, about 2 to 4 weeks after the vaccination, erythema around an area of induration appears. Approximately at the site of prick of injection a nodule shows up. Within 3 to 10 days time, it softens giving rise to a pustule. Bursting of the pustule in about 2 to 5 days after its appearance results in an ulcer 4 to 8 mm in size. This painless...

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Anisakiasis, firstly described in 1960s in the Netherlands, is a fish-borne parasitic disease caused by the consumption of raw or undercooked fish or cephalopods contaminated by third stage (13) larvae of the Anisakidae family, in particular Anisakis simplex (As), A. pegreffii and Pseudoterranova decipiens. Every year, approximately 20,000 cases of anisakiasis were reported worldwide, over 90% ...

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The current role of metformin in the management of infertility

In 1935, Drs Irving Stein and Michael Leventhal were the first to report the association of amenorrhoea, hirsutism, obesity, and infertility; a syndrome that is currently known as the polycystic ovary syndrome (PCOS). The PCOS is considered one of the commonest endocrinopathies that affect between 5 to 10 percent of women of reproductive age (1). The syndrome is also the commonest cause of infe...

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عنوان ژورنال:
journal of research in medical sciences

جلد ۱۹، شماره ۷، صفحات ۰-۰

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